Staff of Domination, Nyxbloom Ancient, Fatestitcher, and Karoo

Prerequisites

• Staff of Domination on the battlefield
• Nyxbloom Ancient on the battlefield
• Fatestitcher on the battlefield
• Karoo on the battlefield

Steps

1. Activate Karoo by tapping it, adding due to Nyxbloom Ancient Activate Fatestitcher by tapping it, untapping Karoo Activate Staff of Domination's third ability by paying and tapping it, untapping Fatestitcher
2. Activate Staff of Domination's first ability by paying , untapping it
3. Repeat

Results

• Infinite card draw
• Infinite colorless mana
• Infinite draw triggers
• Infinite lifegain
• Infinite lifegain triggers
• Infinite white mana
• Infinite mana permanents you control can produce
• Infinite untap of permanents you control