Mairsil, the Pretender, Spikeshot Elder, and Tree of Perdition

Prerequisites

• Mairsil, the Pretender on the battlefield
• Spikeshot Elder in exile
• Tree of Perdition in exile
• undefined available

Steps

1. Activate Mairsil using Tree of Perdition's ability by tapping it, exchanging target opponent's life total with Mairsil's toughness
2. Activate Mairsil using Spikeshot Elder's ability by paying , dealing damage equal to Mairsil's power to the opponent
3. The opponent loses the game due to having zero or less life

Results

• Target opponent loses the game