Vilis, Broker of Blood, Curse of Fool's Wisdom, and Vizkopa Guildmage

Prerequisites

• Vilis, Broker of Blood on the battlefield
• Curse of Fool's Wisdom on the battlefield
• Vizkopa Guildmage on the battlefield
• Curse of Fool's Wisdom attached to you
• The number of cards in your library is at least equal to the highest life total among opponents
• Your life total is at least 3
• available

Steps

1. Activate Vizkopa Guildmage's second ability by paying , creating a triggered ability that will cause opponents to lose life each time you gain life this turn
2. Activate Vilis by paying and 2 life, targeting any creature
3. Vilis triggers, causing you to draw two cards
4. Curse of Fool's Wisdom triggers twice
5. Resolve one Curse of Fool's Wisdom trigger, losing 2 life and gaining 2 life
6. Vilis and Vizkopa Guildmage's ability trigger
7. Resolve the Vizkopa Guildmage's ability's trigger, causing each opponent to lose 2 life
8. Resolve the Vilis trigger, drawing two cards
9. Repeat from step 4

Results

• Infinite card draw
• Infinite draw triggers
• Infinite lifegain triggers
• Near-infinite damage
• Near-infinite lifegain
• Near-infinite lifeloss