Niv-Mizzet, the Firemind, Exquisite Blood, and Lich's Mastery

Prerequisites

• Niv-Mizzet, the Firemind on the battlefield
• Exquisite Blood on the battlefield
• Lich's Mastery on the battlefield
• You have a way to draw a card

Steps

1. Draw a card
2. Niv-Mizzet triggers, dealing 1 damage to an opponent
3. Exquisite Blood triggers, causing you to gain 1 life
4. Lich's Mastery's first ability triggers, causing you to draw a card
5. Repeat from step 2

Results

• Infinite card draw
• Infinite draw triggers
• Near-infinite damage
• Near-infinite lifegain
• Near-infinite lifegain triggers