Gretchen Titchwillow, Amulet of Vigor, Biomancer's Familiar, and Simic Growth Chamber

Prerequisites

• Gretchen Titchwillow on the battlefield
• Amulet of Vigor on the battlefield
• Biomancer's Familiar on the battlefield
• Simic Growth Chamber in hand

Steps

1. Play Simic Growth Chamber
2. Simic Growth Chamber enters the battlefield, triggering itself and Amulet of Vigor
3. Resolve the Amulet of Vigor trigger, untapping Simic Growth Chamber
4. Activate Simic Growth Chamber by tapping it, adding
5. Resolve the Simic Growth Chamber trigger from step 2, returning itself to your hand from the battlefield
6. Activate Gretchen Titchwillow by paying , causing you to draw a card and put Simic Growth Chamber from your hand onto the battlefield
7. Repeat from step 2

Results

• Infinite card draw
• Infinite draw triggers
• Near-infinite landfall triggers