Yawgmoth, Thran Physician, Mikaeus, the Unhallowed, and Ayara, First of Locthwain

Prerequisites

• Yawgmoth, Thran Physician on the battlefield
• Mikaeus, the Unhallowed on the battlefield
• Ayara, First of Locthwain on the battlefield
• Your life total is at least 2
• You control at least one additional nontoken non-Human creature with toughness two or greater

Steps

1. Activate Yawgmoth by paying 1 life and sacrificing Ayara, targeting any other nontoken non-Human creature you control
2. Ayara dies, triggering its undying ability, returning it from your graveyard to the battlefield with a +1/+1 counter on it
3. Ayara enters the battlefield, causing each opponent to lose 1 life and you to gain 1 life
4. Resolve the Yawgmoth ability from step 1, putting a -1/-1 counter on the additional creature and causing you to draw a card
5. Activate Yawgmoth by paying 1 life and sacrificing the additional creature, targeting Ayara
6. The creature dies, triggering its undying ability, returning it from your graveyard to the battlefield with a +1/+1 counter on it
7. If the creature was black, it enters the battlefield, triggering Ayara, causing each opponent to lose 1 life and you to gain 1 life
8. Resolve the Yawgmoth ability, putting a -1/-1 counter on Ayara and causing you to draw a card
9. Repeat

Results

• Infinite card draw
• Infinite draw triggers
• Near-infinite death triggers
• Near-infinite ETB
• Near-infinite lifegain
• Near-infinite lifegain triggers
• Near-infinite lifeloss
• Near-infinite LTB
• Near-infinite sacrifice triggers