Chain of Acid, and Professor Onyx

Prerequisites

• Chain of Acid in hand
• Professor Onyx on the battlefield
• You control an indestructible noncreature permanent
• available

Steps

1. Cast Chain of Acid for targeting an indestructible noncreature permanent you control
2. Professor Onyx triggers, causing each opponent to lose 2 life and you to gain 2 life
3. Resolve Chain of Acid, failing to destroy the target and copying Chain of Acid targeting the same permanent
4. Repeat from step 2

Results

• Infinite lifegain
• Infinite lifegain triggers
• Infinite lifeloss
• Infinite magecraft triggers