Hapatra, Vizier of Poisons, Yawgmoth, Thran Physician, and Obelisk Spider

Prerequisites

• Hapatra, Vizier of Poisons on the battlefield
• Yawgmoth, Thran Physician on the battlefield
• Obelisk Spider on the battlefield
• undefined

Steps

1. Activate Yawgmoth by paying 1 life and sacrificing a creature, targeting any creature an opponent controls, putting a -1/-1 counter on a creature an opponent controls, and causing you to draw a card
2. Hapatra and Obelisk Spider's second abilities trigger
3. Resolve the Hapatra trigger, creating a 1/1 Snake creature token
4. Resolve the Obelisk Spider trigger, causing you to gain 1 life and each opponent to lose 1 life
5. Repeat

Results

• Near-infinite lifeloss
• Near-infinite lifegain triggers
• Near-infinite ETB
• Near-infinite LTB
• Near-infinite death triggers
• Near-infinite sacrifice triggers
• Near-infinite card draw
• Near-infinite draw triggers
• Destroy all creatures opponents control
• Destroy any creature that enters the battlefield under an opponent's control
• Infinite -1/-1 counters