Biorhythm, and Nevinyrral, Urborg Tyrant

Prerequisites

• Biorhythm in hand
• Nevinyrral, Urborg Tyrant on the battlefield
• available

Steps

1. Kill Nevinyrral
2. When it dies, it triggers, causing you to pay to destroy all artifacts, creatures and enchantments
3. Cast Biorhythm by paying its mana cost, causing each player's life total to become equal to the number of creatures they control
4. Each player that controls no creatures loses the game due to having 0 life

Results

• Draw the game
• Each opponent loses the game