Vilis, Broker of Blood, Niv-Mizzet, the Firemind, and Horizon Chimera

Prerequisites

• Vilis, Broker of Blood on the battlefield
• Niv-Mizzet, the Firemind on the battlefield
• Horizon Chimera on the battlefield
• You have a way to draw a card

Steps

1. Draw a card
2. Niv-Mizzet and Horizon Chimera trigger
3. Resolve the Horizon Chimera trigger, causing you to gain 1 life
4. Resolve the Niv-Mizzet trigger, dealing 1 damage to you
5. Vilis triggers, causing you to draw a card
6. Repeat from step 2

Results

• Infinite card draw
• Infinite draw triggers
• Near-infinite lifegain triggers