Minsc & Boo, Timeless Heroes, Malignus, and Solphim, Mayhem Dominus

Prerequisites

• Minsc & Boo, Timeless Heroes on the battlefield
• Malignus on the battlefield
• Solphim, Mayhem Dominus on the battlefield
• Minsc & Boo has at least two loyalty counters on it

Steps

1. Activate Minsc & Boo's second loyalty ability by removing two loyalty counters from it, sacrificing Malignus and dealing damage equal to two times Malignus's power to target opponent
2. The opponent loses the game due to having zero or less life

Results

• Near-infinite damage to target opponent
• Target opponent loses the game