Staff of Domination, Nyxbloom Ancient, Karoo, and Vizier of Tumbling Sands

Prerequisites

• Staff of Domination on the battlefield
• Nyxbloom Ancient on the battlefield
• Karoo on the battlefield
• Vizier of Tumbling Sands on the battlefield

Steps

1. Activate Karoo by tapping it, adding due to Nyxbloom Ancient Activate Vizier of Tumbling Sands by tapping it, untapping Karoo Activate Staff of Domination's third ability by paying and tapping it, untapping Vizier of Tumbling Sands
2. Activate Staff of Domination's first ability by paying , untapping it
3. Repeat

Results

• Infinite card draw
• Infinite colorless mana
• Infinite draw triggers
• Infinite lifegain
• Infinite lifegain triggers
• Infinite white mana
• Infinite mana permanents you control can produce
• Infinite untap of permanents you control