Ezio Auditore da Firenze, and Magister Sphinx

Prerequisites

• Ezio Auditore da Firenze on the battlefield
• Magister Sphinx in hand
• Ezio does not have summoning sickness
• An opponent cannot block Ezio
• available

Steps

1. Cast Magister Sphinx by paying
2. When Magister Sphinx enters the battlefield, it triggers, causing an opponent's life total to become 10
3. Deal combat damage to that opponent using Ezio
4. Ezio triggers, causing you to pay to have that opponent lose the game

Results

• Near-infinite lifeloss for target opponent
• Target opponent loses the game