Yawgmoth, Thran Physician, The Locust God, and Shabraz, the Skyshark

Prerequisites

• Yawgmoth, Thran Physician on the battlefield
• The Locust God on the battlefield
• Shabraz, the Skyshark on the battlefield
• Your life total is at least 2
• You control at least one additional creature

Steps

1. Activate Yawgmoth's first ability by paying 1 life and sacrificing another creature, causing you to draw a card and allowing you to put a -1/-1 counter on up to one creature
2. The Locust God and Shabraz trigger
3. Resolve the Locust God trigger, creating a 1/1 Insect creature token with flying and haste
4. Resolve the Shabraz trigger, causing you to gain 1 life and put a +1/+1 counter on it
5. Repeat

Results

• Infinite card draw
• Near-infinite lifegain triggers
• Near-infinite ETB
• Infinite draw triggers
• Near-infinite LTB
• Near-infinite death triggers
• Near-infinite sacrifice triggers
• Near-infinite +1/+1 counters on Shabraz
• Near-infinite -1/-1 counters