Biorhythm, and Nevinyrral's Disk

Prerequisites

• Biorhythm in hand
• Nevinyrral's Disk on the battlefield
• available

Steps

1. Activate Nevinyrral's Disk by paying and tapping it, destroying all artifacts, enchantments and creatures
2. Cast Biorhythm by paying its mana cost, causing each player's life total to become equal to the number of creatures they control
3. Each player that controls no creatures loses the game due to having 0 life

Results

• Draw the game
• Each opponent loses the game